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Vaccine Progress, Approval, and Deployment

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yorksrob

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It looks as though "The Moral Maze" on Radio 4 will be investigating the arguments around community vaccination tonight. I wonder if they'll come up with anything that we haven't discussed on here !
 
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ainsworth74

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All booked for my first and second jabs now. But like @Darandio my only offers were flaming miles away (I've ended up going to Washington and York) but as I have a car and a boss who is happy for us to take time out of the workday to get vaccinated it's irritation rather than a potential show stopper. It does seem weird that there were no appointments at all on Teesside though through the NHS booking system.
 

NorthOxonian

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All booked for my first and second jabs now. But like @Darandio my only offers were flaming miles away (I've ended up going to Washington and York) but as I have a car and a boss who is happy for us to take time out of the workday to get vaccinated it's irritation rather than a potential show stopper. It does seem weird that there were no appointments at all on Teesside though through the NHS booking system.
Apparently the vaccination centre at the Riverside Stadium only has the AstraZeneca, which they aren't giving to under 40s, and I guess the knock on effects from that will probably be messing with all of Teesside. The MP for Redcar raised it in Parliament yesterday so you would hope something gets done about it.
 

Darandio

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All booked for my first and second jabs now. But like @Darandio my only offers were flaming miles away (I've ended up going to Washington and York) but as I have a car and a boss who is happy for us to take time out of the workday to get vaccinated it's irritation rather than a potential show stopper. It does seem weird that there were no appointments at all on Teesside though through the NHS booking system.

A pain in the arse is what it is. It's as if there is no hospital in Redcar dishing vaccines out on a daily basis.

Apparently the vaccination centre at the Riverside Stadium only has the AstraZeneca, which they aren't giving to under 40s, and I guess the knock on effects from that will probably be messing with all of Teesside. The MP for Redcar raised it in Parliament yesterday so you would hope something gets done about it.

I'm over 40 and have never been offered a shot at the Riverside!
 

ainsworth74

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A pain in the arse is what it is. It's as if there is no hospital in Redcar dishing vaccines out on a daily basis.

Absolutely and I know they're doing Pfizer because that's where my mum went and got jabbed with Pfizer!!

The MP for Redcar raised it in Parliament yesterday so you would hope something gets done about it.
Hopefully so! I'm irritated by having to traipse around the North East but it isn't a show stopper for me. But then I have access to a car, can afford the petrol, have a supportive employer and don't have childcare or other issues to worry about so can be very flexible!
 

yorkie

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24 currently in hospital in Bolton with COVID, compared to 12 a week ago is a 100% increase week on week. If that trend continues it would be extremely worrying...
I really don't understand what you are saying but what matters is that the vaccines are highly effective against severe disease and relegate Sars-CoV-2 to a minor illness.

Apparently the vaccination centre at the Riverside Stadium only has the AstraZeneca, which they aren't giving to under 40s, and I guess the knock on effects from that will probably be messing with all of Teesside. The MP for Redcar raised it in Parliament yesterday so you would hope something gets done about it.
That would be bonkers as the supposed risk from AZ is absolutely miniscule and negligible, and there is growing evidence that viral vector vaccines could actually be "safer" for younger males than mRNA vaccines (with potentially the mRNA vaccines potentially being "safer" than viral vector vaccines for younger females)
 

Crossover

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All booked for my first and second jabs now. But like @Darandio my only offers were flaming miles away (I've ended up going to Washington and York) but as I have a car and a boss who is happy for us to take time out of the workday to get vaccinated it's irritation rather than a potential show stopper. It does seem weird that there were no appointments at all on Teesside though through the NHS booking system.
It is odd - when I booked mine, there were at least 3 places within 10 mins drive from where I live. I tried it from work, some 20 miles away (Oldham) and was largely offered Sheffield, other side of Manchester and the same ones near home and Leeds wasn't much better,to be honest. Seems to be a bit of a lottery
 

Pakenhamtrain

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Down here in Australia we have been the victim of our own success in ridding the joint of covid. No covid no one wants a jab.

Funny enough now there's covid in the community there's suddenly lines put the door of the vaccination centres.
 

matt

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I was going to the local ish vaccination centre but they are now doing it more close to me so I have booked there instead.
 

Pete_uk

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Thanks for the update. I checked this morning and it still said 32 but see it has changed to 30 now. I can get involved.

Not that I am overly enthusiastic to do so.
Why? It's all good.

You can then go around with a hidden glow of smugness!
If the nurse is anything like mine you will be left wondering if you even had a jab.
 

birchesgreen

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Why? It's all good.

You can then go around with a hidden glow of smugness!
If the nurse is anything like mine you will be left wondering if you even had a jab.
Yes you can post a pic of your vaccination card on social media like losers do.

Got me quite a lot of likes on Facebook when I posted mine earlier.
 

The Ham

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I really don't understand what you are saying but what matters is that the vaccines are highly effective against severe disease and relegate Sars-CoV-2 to a minor illness.


That would be bonkers as the supposed risk from AZ is absolutely miniscule and negligible, and there is growing evidence that viral vector vaccines could actually be "safer" for younger males than mRNA vaccines (with potentially the mRNA vaccines potentially being "safer" than viral vector vaccines for younger females)

According to a report I heard in the BBC the risk of getting a blood clot after having the AZ jab for someone under 30 was the same as the risk from driving 250 miles.

Even if that risk was miss calculated by a factor of 3 that's still likely to be lower than many people drive in 6 weeks with little or no concern about the risk.

It's also a risk that is rarely repeated (even if we have to have a vaccine each year is a once a year thing), rather than an ongoing risk, as if you drive another 250/750 miles you have the same risk again (typically over 30 or 10 lots of risk).

On an unrelated point I've heard that the vaccine changes your DNA, so given I was given the Pfizer vaccine when can I expect to be able to speak German?!?
 

35B

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According to a report I heard in the BBC the risk of getting a blood clot after having the AZ jab for someone under 30 was the same as the risk from driving 250 miles.

Even if that risk was miss calculated by a factor of 3 that's still likely to be lower than many people drive in 6 weeks with little or no concern about the risk.

It's also a risk that is rarely repeated (even if we have to have a vaccine each year is a once a year thing), rather than an ongoing risk, as if you drive another 250/750 miles you have the same risk again (typically over 30 or 10 lots of risk).

On an unrelated point I've heard that the vaccine changes your DNA, so given I was given the Pfizer vaccine when can I expect to be able to speak German?!?
Never, because the vaccine does not change your DNA.
 

takno

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According to a report I heard in the BBC the risk of getting a blood clot after having the AZ jab for someone under 30 was the same as the risk from driving 250 miles.

Even if that risk was miss calculated by a factor of 3 that's still likely to be lower than many people drive in 6 weeks with little or no concern about the risk.

It's also a risk that is rarely repeated (even if we have to have a vaccine each year is a once a year thing), rather than an ongoing risk, as if you drive another 250/750 miles you have the same risk again (typically over 30 or 10 lots of risk).

On an unrelated point I've heard that the vaccine changes your DNA, so given I was given the Pfizer vaccine when can I expect to be able to speak German?!?
I haven't heard the stat about driving 250 miles, but if it is accurate then it's likely to be 250 miles in a single sitting rather than cumulative. Most people don't ever do that
 

jfollows

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I haven't heard the stat about driving 250 miles, but if it is accurate then it's likely to be 250 miles in a single sitting rather than cumulative. Most people don't ever do that
I heard the stat about driving 250 miles several weeks ago, but then couldn't find it again, so I wondered if my memory was faulty. I think it's a message that ought to have been broadcast more widely than it was.
I think that politicians across the world have reacted appallingly badly to the facts behind the AZ vaccine because, as this exemplifies, the risks can be compared with "trivial" things like this, or the risk of taking paracetamol, to name something else.
I received the Pfizer vaccine, and I'm not in the "risk" group for the AZ vaccine, but I'd like to think that I'd have seen through the fog and been happy to have taken it if I were.
Sadly, many more people are going to die from Covid-19 than would otherwise have been the case thanks to the incompetence of messaging, primarily from politicians.

EDIT I believe the 250 miles is simply a cumulative mileage and a cumulative risk from driving a total of 250 miles, not related to a single journey, but simply derived from taking the total number of miles driven by everyone divided by the number of serious injuries that happen.
 

takno

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I heard the stat about driving 250 miles several weeks ago, but then couldn't find it again, so I wondered if my memory was faulty. I think it's a message that ought to have been broadcast more widely than it was.
I think that politicians across the world have reacted appallingly badly to the facts behind the AZ vaccine because, as this exemplifies, the risks can be compared with "trivial" things like this, or the risk of taking paracetamol, to name something else.
I received the Pfizer vaccine, and I'm not in the "risk" group for the AZ vaccine, but I'd like to think that I'd have seen through the fog and been happy to have taken it if I were.
Sadly, many more people are going to die from Covid-19 than would otherwise have been the case thanks to the incompetence of messaging, primarily from politicians.

EDIT I believe the 250 miles is simply a cumulative mileage and a cumulative risk from driving a total of 250 miles, not related to a single journey, but simply derived from taking the total number of miles driven by everyone divided by the number of serious injuries that happen.
Ah, if it's about total risk rather than risk of clot then that would make sense. Obviously the risk of death from AZ is absolutely tiny, particularly if you're male. On the other hand the risk of an unpleasant reaction from jt if you're under 60 with a working immune system is really quite high. If I was in my 20s with an absolutely tiny risk from Covid, I reckon the high likelihood of at least a day of feeling really quite ill from the vaccine would put me off AZ
 

jfollows

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Having looked slightly further, I believe the "250 miles" figure is a comparison with the risk of dying in both cases, from a cumulative driving mileage or from blood clots caused by the AZ vaccine. The incidence of blood clots caused by the AZ vaccine appears to be about 4 times greater than this, but 75% of people affected don't die. And, of course, these figures are for a random population sample, however even in this women are affected 2.5 times as badly as men, but they don't relate to age of people vaccinated - as indeed the driving deaths don't relate to age of the drivers.

A while back I quoted MD from Private Eye that essentially there's a 1 in a million risk associated with vaccines in broad generality, which also is the risk from taking medication such as paracetamol in broad generalisation. I'm not sure how useful these generalisations are, but perhaps at least they set a context - that there's nothing radically unusual or different about the bad effects of the AZ vaccine.
 

35B

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Ah, if it's about total risk rather than risk of clot then that would make sense. Obviously the risk of death from AZ is absolutely tiny, particularly if you're male. On the other hand the risk of an unpleasant reaction from jt if you're under 60 with a working immune system is really quite high. If I was in my 20s with an absolutely tiny risk from Covid, I reckon the high likelihood of at least a day of feeling really quite ill from the vaccine would put me off AZ
It might, which is why the questions about the population effect do matter in influencing individuals' decisions.
 

Djgr

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Ah, if it's about total risk rather than risk of clot then that would make sense. Obviously the risk of death from AZ is absolutely tiny, particularly if you're male. On the other hand the risk of an unpleasant reaction from jt if you're under 60 with a working immune system is really quite high. If I was in my 20s with an absolutely tiny risk from Covid, I reckon the high likelihood of at least a day of feeling really quite ill from the vaccine would put me off AZ
I think you exaggerate both "unpleasant' and "quite high".
 

WelshBluebird

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On the other hand the risk of an unpleasant reaction from jt if you're under 60 with a working immune system is really quite high
Sorry but no it isn't "quite high" at all.
You know what the most common side effects are - something akin to a hangover (achy, feeling tired, maybe a bit of a headache / head cold). You know the thing that people give themselves voluntary all of the time.
The "risk" of "unpleasant" reactions (or at least serious ones) is tiny. Even smaller than your risk of getting seriously ill from Covid.
 

takno

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I think you exaggerate both "unpleasant' and "quite high".
I'm going from a sample of everybody I know who's had it, which gives roughly 95% of people having something unpleasant enough to completely throw them for a day. The government figures suggest around a third, but they are based on responses from older people who appear to have been hit much less hard
 

Mintona

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In a complete about turn from yesterday, I have now had the vaccine and can no longer feel my arm.
 

Silver Cobra

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I had my first vaccine today (which was Pfizer). I must admit, a few minutes after it was given, I came over with the cold sweats, dizzy head and quite extreme 'pins and needles' in my left arm. Thankfully after another 5 or so minutes it all subsided, and now I just have the sore arm around the injection point. As someone who suffers quite badly from anxiety, I imagine that was largely the root cause to what happened to me. Here's hoping all remains OK over the next few days.
 

35B

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I'm going from a sample of everybody I know who's had it, which gives roughly 95% of people having something unpleasant enough to completely throw them for a day. The government figures suggest around a third, but they are based on responses from older people who appear to have been hit much less hard
My wife and I are both in our mid 40s; we both had the AZ vaccine and a spell about 48 hours after the jabs lasting a couple of days when we felt like we were struggling with a heavy cold. Colleagues (similar-ish ages) have had a range of reactions from being completely wiped out to nothing noticeable. I regard those side effects as a low price to pay for something that is of potentially very great benefit to me, bearing in mind that the probability of my being seriously ill with Covid is very low, but the consequences of that to me are extremely serious; something that the normal probability based approach doesn't consider particularly well.
 

GB

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I had my first vaccine today (which was Pfizer). I must admit, a few minutes after it was given, I came over with the cold sweats, dizzy head and quite extreme 'pins and needles' in my left arm. Thankfully after another 5 or so minutes it all subsided, and now I just have the sore arm around the injection point. As someone who suffers quite badly from anxiety, I imagine that was largely the root cause to what happened to me. Here's hoping all remains OK over the next few days.

I was similar. I had my first jab last week in the afternoon. It was the Pfizer but thankfully didn't feel any side effects other than an achy arm until the next morning.
 

Crossover

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In a complete about turn from yesterday, I have now had the vaccine and can no longer feel my arm.

I had my first vaccine today (which was Pfizer). I must admit, a few minutes after it was given, I came over with the cold sweats, dizzy head and quite extreme 'pins and needles' in my left arm. Thankfully after another 5 or so minutes it all subsided, and now I just have the sore arm around the injection point. As someone who suffers quite badly from anxiety, I imagine that was largely the root cause to what happened to me. Here's hoping all remains OK over the next few days.
Another hand up for being jabbed today. Also Pfizer and I was one of the last of the day at the surgery I was at. All very well organised

Felt very little of the injection itself, followed by a little ache soon after. Arm is now rather achy (feels bruised) around the injection site but otherwise, so far so good
 

philosopher

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I was similar. I had my first jab last week in the afternoon. It was the Pfizer but thankfully didn't feel any side effects other than an achy arm until the next morning.
I had the Pfizer jab last Thursday lunchtime and had a sore arm from Thursday afternoon until Saturday lunchtime. I did feel tired too on the Thursday and Friday but I am not sure whether that was actually the vaccine or physiological.
 

Bald Rick

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I had my first jab the other week in the morning, and had 8 pints of various beers in the afternoon / evening.

Felt rubbish the next day. Bloody vaccine.
 

TravelDream

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I had the vaccine just over a week ago.
I got a text the evening before saying I had an appointment I didn't know about the next morning. I live in Wales so there is no online appointment system and people are supposed to be sent appointments through the post.
I had the Pfizer one and have to say I had basically no side-effects at all. Maybe my arm was the tiniest bit sore at the injection site the next day, but nothing noticeable.

That would be bonkers as the supposed risk from AZ is absolutely miniscule and negligible, and there is growing evidence that viral vector vaccines could actually be "safer" for younger males than mRNA vaccines (with potentially the mRNA vaccines potentially being "safer" than viral vector vaccines for younger females)
Is there evidence for this? I try to keep up on vaccine news, but the volume is so great it is impossible.
I have seen articles saying the risk of viral vector vaccines like the Oxford one might be greater for women, but I haven't seen any articles saying they might be safer for males though.
 
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