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There was some research done on this in the 80s specifically in a railway context. I found it while researching my degree dissertation. From memory, the key thing is that mixed case allows those with sight difficulties to more easily distinguish letters and hence read words. You'd think that...

For a real surprise, try the Leonardo Express service from da Vinci airport to Roma Termini. It makes London Overground services look high speed - there's a short section that just about reaches 100kmph. Carriages are clean and modern but thanks to wonderful diagramming they arrive in Termini...