To late, Nicola had already seen it and has been talking about 4 plus...
This is now just political games, surely? It's a joke, just not a funny one.
Can't deny that's a good suggestion!
They'll probably need their second dose first, so yes by mid-late January we'd hope for some effect. 500,000 vaccinated is of course significantly higher than any of the measures of deaths with Covid (highest excess death value is around 81,000). I do also think infections could have peaked by the end of January, given how high the rate is currently and the potential for an immunity buffer being established through just the second wave's effects so far.
Given that only first doses are still being given, the rate will need to at least potentially double for quite along time or else the rate at which first jabs are given will need to decrease to match capacity.
So much so that an "expert" on the field, by the name of Tony Blair, is arguing for this approach:
www.bbc.co.uk
So much so that an "expert" on the field, by the name of Tony Blair, is arguing for this approach:
Coronavirus: Vaccinate more people with one dose, urges Tony Blair
The ex-PM says the UK could exit Covid restrictions earlier if stocks were not held back for a second jab.
I agree, but I think more voices need to be calling for this fast so doses are not wasted on the same people if one dose definitely is enough.
Pfizer says the data only shows a single dose of the vaccine is 52% effective. which would struggle to be approved (50% cut off) and would store up huge problems for later due to lower effectiveness.
It isn't though, which is why there aren't more voices as many potential voices would fact check first.
As it is contradicted by phase 3 clinical trial data don't expect it to go far. Blair should be apologising for spouting untruths in the national media.
Pfizer says the data only shows a single dose of the vaccine is 52% effective. which would struggle to be approved (50% cut off) and would store up huge problems for later due to lower effectiveness.
The second dose increases the effectiveness by 80+% compared to a single dose.
See BMJ coverage here:
Covid-19: Pfizer vaccine efficacy was 52% after first dose and 95% after second dose, paper shows
The Pfizer and BioNTech covid-19 vaccine may provide some early protection, starting 12 days after the first dose, the peer reviewed results of a phase III trial have found. The study, published in the New England Journal of Medicine ,1 found that vaccine efficacy between the first and second...www.bmj.com
== Doublepost prevention - post automatically merged: ==
It isn't though, which is why there aren't more voices as many potential voices would fact check first.
== Doublepost prevention - post automatically merged: ==
As it is contradicted by phase 3 clinical trial data don't expect it to go far. Blair should be apologising for spouting untruths in the national media.
Pfizer says the data only shows a single dose of the vaccine is 52% effective. which would struggle to be approved (50% cut off) and would store up huge problems for later due to lower effectiveness.
The second dose increases the effectiveness by 80+% compared to a single dose.
See BMJ coverage here:
Covid-19: Pfizer vaccine efficacy was 52% after first dose and 95% after second dose, paper shows
The Pfizer and BioNTech covid-19 vaccine may provide some early protection, starting 12 days after the first dose, the peer reviewed results of a phase III trial have found. The study, published in the New England Journal of Medicine ,1 found that vaccine efficacy between the first and second...
== Doublepost prevention - post automatically merged: ==
It isn't though, which is why there aren't more voices as many potential voices would fact check first.
== Doublepost prevention - post automatically merged: ==
As it is contradicted by phase 3 clinical trial data don't expect it to go far. Blair should be apologising for spouting untruths in the national media.
2*52 is more than 1*80 though...Pfizer says the data only shows a single dose of the vaccine is 52% effective. which would struggle to be approved (50% cut off) and would store up huge problems for later due to lower effectiveness.
The second dose increases the effectiveness by 80+% compared to a single dose.
See BMJ coverage here:
Covid-19: Pfizer vaccine efficacy was 52% after first dose and 95% after second dose, paper shows
The Pfizer and BioNTech covid-19 vaccine may provide some early protection, starting 12 days after the first dose, the peer reviewed results of a phase III trial have found. The study, published in the New England Journal of Medicine ,1 found that vaccine efficacy between the first and second...
== Doublepost prevention - post automatically merged: ==
It isn't though, which is why there aren't more voices as many potential voices would fact check first.
== Doublepost prevention - post automatically merged: ==
As it is contradicted by phase 3 clinical trial data don't expect it to go far. Blair should be apologising for spouting untruths in the national media.
True, but I think the absolute number matters here; 200 identical people with 52% protection drops the number of people at risk of hospitalisation by half, whereas 100 with 95% (from a double dose) and 100 (no dose) with 0% drop it by 42%.
Indeed you only get an extra 0.8 fold benefit not 1.0 from the second dose.
1. It is being targeted at those with high risk of hospitalisation so all those people aren't identical
Agree.
It might increase the herd immunity threshold but as it seems to be spreading fast at the moment it might not necessarily be any slower to reach that level. Besides they should really lift everything once the most vulnerable people have been vaccinated, even if herd immunity overall hasn't been reached at that time.
With the Pfizer vaccine 90% effectiveness is achieved 7days post second dose and 95% 7days post second dose. Hence if the second dose is exactly 3 weeks after the first, then there is a 5 week lag till peak effectiveness is achieved after the first dose.
Immunologists tend to classify immunity by previous infection and vaccination differently as the latter tends to provide far better and longer lasting immunity.
