Don't know about drivers but I know Piccadilly guards don't sign anywhere north of Castlefield Junction (at least they didn't in 2008), so there is no chance they will work any of the Blackpool services.
As for traction from Manchester to Blackpool, the only second/third generation DMUs I know to have traversed this route are: 142 (not so many mind), 150, 153 (used to be a booked strengthening on an early evening service from Stockport Mon-Fri, hasn't run since December '08), 156, 158 (semi-regular up until about 2003 - think some were booked in pre-175 days, then once the 175s arrived they usually stood in whenever there was a diagram inbalance or a 175 shortage), 175 (up until December 2006), 180 (December 2008-December 2011) and 185 (from December 2006).
Anyone remember seeing/hearing of TPE using one of their own 158s on an Airport-Blackpool service? (or Barrow/Windermere for that matter?)