Not from that point of view specifically. Just in my mind it seems a bit odd to bodge up 5 sets when it would be possible to bodge up less/none, but that may just be my OCD
It does seem daft that Virgin, Voyager Leasing and the DfT couldn't have recognised that Virgin desired an all 5-car fleet at the time that the 221 fleet was carved up between the West Coast and new Crosscountry franchise in 2007/8, which would have avoided all this subsequent jiggery-pokery and not resulted in the slightly absurd situation where two driving cars from a capacity stretched fleet will have sat unused for seven years by the time that they are brought back into service.
In terms of slightly unusual formations, the reformation of three 221 units for Crosscountry (221136/140 and 144) will also presumably result in one 4-car set that lacks the large Coach D luggage area, unless part of the reason for the removal of 60986 from 221136 this far ahead of 221144's re-entry to service is to allow the installation of such.