In 1919 the
Radcliffe Infirmary purchased the Manor House estate in Headington. The Infirmary site was already overcrowded, and they had been asked to provide sanatorium accommodation for tuberculosis sufferers. They had applied to the Radcliffe Trustees for the use of some of the Observatory land, but without success. A public appeal for funds was launched, and much of the purchase price came from the British Red Cross as part of the winding up of monies raised during the First World War; it was proposed that the new hospital should serve as a war memorial.
Roads and drainage for a tuberculosis hospital were laid, but financial difficulties intervened. In the event, the first hospital use of the site was when the Preliminary Training School of the newly established School of Nursing took up residence in the Manor House in 1922. The Ministry of Health finally approved the plans for the hospital for tuberculosis cases, and the Osler Pavilion opened in 1927, named after Sir William Osler (1849 - 1919), Regius Professor of Medicine.