Jozhua
Established Member
- Joined
- 6 Jan 2019
- Messages
- 1,891
There seems to be a lot of holes in our testing and reporting of both cases and reporting of deaths due to COVID-19. This has made coming out with more concrete spread/death rates difficult.
Having this data is important, as it allows health officials to know what policies to enact and the exact risk to the public. Up to 80% of cases are estimated to be asymptomatic, with only 20% showing symptoms. Testing of pregnant women coming to give birth in an NYC hospital may shed some light on this situation:
New England Journal of Medicine - Universal Screening for SARS-CoV-2 in Women Admitted for Delivery
If this turns out to be the case, deaths may spike for the next month or so, but then the population may gain herd immunity with a much lower human cost associated with it. If not, lockdowns will be necessary to contain the spread, if possible. Then there's the risk of asymptomatic spread, etc...
Really, an antibodies test will help us understand the true scale and come up with better estimates for cases, fatalities and case fatalities.
Also, I've noticed an uptick in the case fatality ratio in the UK, which seems to point to only more serious cases being tested, which means there is an even higher amount going unreported than before. Over the last couple of weeks, case fatality has increased from 5%ish to 20%ish... Also, due to not having a representative sample of the population routinely tested, we can't even rely on the trends of case numbers to try and work out what's going on.
I think the stable linear chart gives a false impression of containment too, as we essentially hit our testing limits to publish about 4-5000 new positive cases a day.
I'd be interested to hear everyone's thoughts, estimations and new data that perhaps samples representitive spreads of the population and sees what proportion is infected, and how many of those go onto develop more severe symptoms. Also can't wait for this antibodies test, although looks like that's going to be May time at the earliest...
Having this data is important, as it allows health officials to know what policies to enact and the exact risk to the public. Up to 80% of cases are estimated to be asymptomatic, with only 20% showing symptoms. Testing of pregnant women coming to give birth in an NYC hospital may shed some light on this situation:
New England Journal of Medicine - Universal Screening for SARS-CoV-2 in Women Admitted for Delivery
Thus, 29 of the 33 patients who were positive for SARS-CoV-2 at admission (87.9%) had no symptoms of Covid-19 at presentation.
Of the 29 women who had been asymptomatic but who were positive for SARS-CoV-2 on admission, fever developed in 3 (10%) before postpartum discharge (median length of stay, 2 days). Two of these patients received antibiotics for presumed endomyometritis (although 1 patient did not have localizing symptoms), and 1 patient was presumed to be febrile due to Covid-19 and received supportive care. One patient with a swab that was negative for SARS-CoV-2 on admission became symptomatic postpartum; repeat SARS-CoV-2 testing 3 days after the initial test was positive.
If this turns out to be the case, deaths may spike for the next month or so, but then the population may gain herd immunity with a much lower human cost associated with it. If not, lockdowns will be necessary to contain the spread, if possible. Then there's the risk of asymptomatic spread, etc...
Really, an antibodies test will help us understand the true scale and come up with better estimates for cases, fatalities and case fatalities.
Also, I've noticed an uptick in the case fatality ratio in the UK, which seems to point to only more serious cases being tested, which means there is an even higher amount going unreported than before. Over the last couple of weeks, case fatality has increased from 5%ish to 20%ish... Also, due to not having a representative sample of the population routinely tested, we can't even rely on the trends of case numbers to try and work out what's going on.
I think the stable linear chart gives a false impression of containment too, as we essentially hit our testing limits to publish about 4-5000 new positive cases a day.
I'd be interested to hear everyone's thoughts, estimations and new data that perhaps samples representitive spreads of the population and sees what proportion is infected, and how many of those go onto develop more severe symptoms. Also can't wait for this antibodies test, although looks like that's going to be May time at the earliest...