Plus the TPWS loops are designed to operate in the right direction by the very nature, so they are totally ineffective if they are driven over in the reverse direction.
Do agree that there are a lot of parallel's between Railway and Aviation (being an aviation enthusiast myself) and spatial awareness is something very easy to lose with no frame of reference, notably being a causal factor in a lot of helicopter accidents in white-out conditions on snow/sand - where the down-draught from the rotor kicks up a fine mist of snow/sand and totally destroys any visual reference, and it is amazing how easily the inner ear can be fooled!
Indeed - I hear that the fixed-base iPilot 737NG simulator in Bluewater, which I plan to go to very soon, gives very pronounced feelings of motion despite there being no movement physically - just what you can see on the display infront of you!