I've never heard of anyone living in Slough. I know quite a few who live "near Windsor" though.
Yep, guilty as charged...
And when it comes to all the talk about "realistic" Elizabeth Line journeys, I think there are a reasonable amount of journeys made into the core from the likes of Maidenhead and Twyford in spite of the faster GWR alternatives, simply to avoid the hassle of changing at Paddington. The least "realistic" part is heading to Abbey Wood. So journeys of an hour or over are quite conceivable.
What might be more conceivable is direct Shenfield-Heathrow, particularly with heavy luggage making the convenience of a direct train easier. That's basically the same as Reading-Abbey Wood at about an hour and 20 minutes, and, if we're including a realism clause, would be my answer.
Honourable mention to the Mildmay Line which is over an hour too.